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Cellular Growth Arrest and Persistence from Enzyme Saturation
Metabolic efficiency depends on the balance between supply and demand of metabolites, which is sensitive to environmental and physiological fluctuations, or noise, causing shortages or surpluses in the metabolic pipeline. How cells can reliably optimize biomass production in the presence of metaboli...
Autores principales: | Ray, J. Christian J., Wickersheim, Michelle L., Jalihal, Ameya P., Adeshina, Yusuf O., Cooper, Tim F., Balázsi, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820279/ https://www.ncbi.nlm.nih.gov/pubmed/27010473 http://dx.doi.org/10.1371/journal.pcbi.1004825 |
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