Cargando…

Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds

Marine natural products (MNPs) are recognized for their structural complexity, diversity, and novelty. The vast majority of MNPs are pharmacologically relevant through their ability to modulate macromolecular targets underlying human diseases. Angiogenesis is a fundamental process in cancer progress...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ebrahim, Hassan Y., El Sayed, Khalid A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820311/ https://www.ncbi.nlm.nih.gov/pubmed/26978377 http://dx.doi.org/10.3390/md14030057

Ejemplares similares

The Discovery of Marine Natural Products with Therapeutic Potential
por: Oliver, J.McConnell, et al.
Publicado: (1994)

Marine fungi: A treasure trove of novel natural products and for biological discovery
por: Kempken, Frank
Publicado: (2023)

In Situ Natural Product Discovery via an Artificial Marine Sponge
por: La Clair, James J., et al.
Publicado: (2014)

An assessment of natural product discovery from marine (sensu strictu) and marine-derived fungi
por: Overy, David P., et al.
Publicado: (2014)

Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities
por: Jaballah, Maiy Y., et al.
Publicado: (2019)

Recent Advances in the Discovery and Development of Marine Microbial Natural Products
por: Xiong, Zhi-Qiang, et al.
Publicado: (2013)

Genome Mining and Synthetic Biology in Marine Natural Product Discovery
por: Costantini, Maria
Publicado: (2020)

Marine fungi in the spotlight: opportunities and challenges for marine fungal natural product discovery and biotechnology
por: Tasdemir, Deniz
Publicado: (2017)

Marine Natural Products with Activities against Prostate Cancer: Recent Discoveries
por: Montuori, Eleonora, et al.
Publicado: (2023)

Natural Products as Antiviral Agents
por: El Sayed, Khalid A.
Publicado: (2000)

Antiangiogenic activity of aplidine, a new agent of marine origin
por: Taraboletti, G, et al.
Publicado: (2004)

Antiangiogenic cancer treatment: The great discovery and greater complexity (Review)
por: Maj, Ewa, et al.
Publicado: (2016)

The Neglected Marine Fungi, Sensu stricto, and Their Isolation for Natural Products’ Discovery
por: Overy, David P., et al.
Publicado: (2019)

Discovery of Marine Natural Products as Promising Antibiotics against Pseudomonas aeruginosa
por: Li, Haoran, et al.
Publicado: (2022)

Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates
por: McCauley, Erin P., et al.
Publicado: (2020)

Antiproliferative and Antiangiogenic Activities of Smenospongine, a Marine Sponge Sesquiterpene Aminoquinone
por: Kong, Dexin, et al.
Publicado: (2011)

Marine Natural Products: A Source of Novel Anticancer Drugs
por: Khalifa, Shaden A. M., et al.
Publicado: (2019)

Marine Natural Product Libraries for High-Throughput Screening and Rapid Drug Discovery
por: Bugni, Tim S., et al.
Publicado: (2008)

Future Directions of Marine Myxobacterial Natural Product Discovery Inferred from Metagenomics
por: Garcia, Ronald, et al.
Publicado: (2018)

Recent advances in the discovery of novel marine natural products and mycosporine-like amino acid UV-absorbing compounds
por: Rosic, Nedeljka N.
Publicado: (2021)

The Marine-Derived Sipholenol A-4-O-3′,4′-Dichlorobenzoate Inhibits Breast Cancer Growth and Motility in Vitro and in Vivo through the Suppression of Brk and FAK Signaling
por: Akl, Mohamed R., et al.
Publicado: (2014)

Quality not Quantity: The Role of Marine Natural Products in Drug Discovery and Reverse Chemical Proteomics
por: Piggott, Andrew M., et al.
Publicado: (2005)

The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase
por: Mudhish, Ethar A., et al.
Publicado: (2022)

High content live cell imaging for the discovery of new antimalarial marine natural products
por: Cervantes, Serena, et al.
Publicado: (2012)

Discovery of novel natural products for mosquito control
por: Engdahl, Cecilia S., et al.
Publicado: (2022)

Discovery of Novel Natural Products with Therapeutic Potential
por: Gullo, Vincent
Publicado: (2013)

Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii
por: Leber, Christopher A., et al.
Publicado: (2020)

Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates
por: Trindade, Marla, et al.
Publicado: (2015)

Antiangiogenic molecules from marine actinomycetes and the importance of using zebrafish model in cancer research
por: Nathan, Jhansi, et al.
Publicado: (2020)

Novel production method of innovative antiangiogenic and antitumor small peptides in Escherichia coli
por: Setrerrahmane, Sarra, et al.
Publicado: (2017)

Genome-Based Studies of Marine Microorganisms to Maximize the Diversity of Natural Products Discovery for Medical Treatments
por: Zhao, Xin-Qing
Publicado: (2011)

Current Status on Marine Products with Reversal Effect on Cancer Multidrug Resistance
por: Abraham, Ioana, et al.
Publicado: (2012)

Natural Marine Antiviral Products
por: Martinez, Maria Jose Abad, et al.
Publicado: (2008)

Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives
por: Mehbub, Mohammad Ferdous, et al.
Publicado: (2014)

Special Issue on Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective
por: Duarte, Noélia
Publicado: (2022)

Antiangiogenic therapy
por: Avitabile, T
Publicado: (2010)

Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe Merr
por: Nassar, Zeyad D, et al.
Publicado: (2011)

Editorial: Are natural products, used as antitumoral/antiangiogenic agents, less toxic than synthetic conventional chemotherapy?
por: Nunez, Cecilia Veronica, et al.
Publicado: (2022)

Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs
por: Arvin-Berod, Marie, et al.
Publicado: (2017)

Marine Spongin: Naturally Prefabricated 3D Scaffold-Based Biomaterial
por: Jesionowski, Teofil, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_mgfqaqg2gbd0ub5bvjqphto9sv