Preparation of Fe(2)O(3)-Clorprenaline/Tetraphenylborate Nanospheres and Their Application as Ion Selective Electrode for Determination of Clorprenaline in Pork

A novel modified ion selective electrode based on Fe(2)O(3)-clorprenaline/tetraphenylborate nanospheres (Fe(2)O(3)-CLPT NSs) as electroactive materials for the determination of clorprenaline hydrochloride (CLP) is described. The α-Fe(2)O(3) nanoparticles (NPs) were prepared by hydrothermal synthesis, then self-assembled on CLP/tetraphenylborate (TPB) to form Fe(2)O(3)-CLPT NSs, which were used as a potentiometric electrode for analyte determination innovatively. The Fe(2)O(3)-CLPT NSs modified electrode exhibited a wider concentration range from 1.0 × 10(−7) to 1.0 × 10(−1) mol/L and a lower detection limit of 3.7 × 10(−8) mol/L compared with unmodified electrodes. The selectivity of the modified electrode was evaluated by fixed interference method. The good performance of the modified electrode such as wide pH range (2.4–6.7), fast response time (15 s), and adequate lifetime (14 weeks) indicate the utility of the modified electrode for evaluation of CLP content in various real samples. Finally, the modified electrode was successfully employed to detect CLP in pork samples with satisfactory results. These results demonstrated the Fe(2)O(3)-CLPT NSs modified electrode to be a functional and convenient method to the field of potentiometry determination of CLP in real samples.