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Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error
Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main ef...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820539/ https://www.ncbi.nlm.nih.gov/pubmed/27020472 http://dx.doi.org/10.1038/ncomms11008 |
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| author | Fan, Qiao Verhoeven, Virginie J. M. Wojciechowski, Robert Barathi, Veluchamy A. Hysi, Pirro G. Guggenheim, Jeremy A. Höhn, René Vitart, Veronique Khawaja, Anthony P. Yamashiro, Kenji Hosseini, S Mohsen Lehtimäki, Terho Lu, Yi Haller, Toomas Xie, Jing Delcourt, Cécile Pirastu, Mario Wedenoja, Juho Gharahkhani, Puya Venturini, Cristina Miyake, Masahiro Hewitt, Alex W. Guo, Xiaobo Mazur, Johanna Huffman, Jenifer E. Williams, Katie M. Polasek, Ozren Campbell, Harry Rudan, Igor Vatavuk, Zoran Wilson, James F. Joshi, Peter K. McMahon, George St Pourcain, Beate Evans, David M. Simpson, Claire L. Schwantes-An, Tae-Hwi Igo, Robert P. Mirshahi, Alireza Cougnard-Gregoire, Audrey Bellenguez, Céline Blettner, Maria Raitakari, Olli Kähönen, Mika Seppala, Ilkka Zeller, Tanja Meitinger, Thomas Ried, Janina S. Gieger, Christian Portas, Laura van Leeuwen, Elisabeth M. Amin, Najaf Uitterlinden, André G. Rivadeneira, Fernando Hofman, Albert Vingerling, Johannes R. Wang, Ya Xing Wang, Xu Tai-Hui Boh, Eileen Ikram, M. Kamran Sabanayagam, Charumathi Gupta, Preeti Tan, Vincent Zhou, Lei Ho, Candice E. H. Lim, Wan'e Beuerman, Roger W. Siantar, Rosalynn Tai, E-Shyong Vithana, Eranga Mihailov, Evelin Khor, Chiea-Chuen Hayward, Caroline Luben, Robert N. Foster, Paul J. Klein, Barbara E. K. Klein, Ronald Wong, Hoi-Suen Mitchell, Paul Metspalu, Andres Aung, Tin Young, Terri L. He, Mingguang Pärssinen, Olavi van Duijn, Cornelia M. Jin Wang, Jie Williams, Cathy Jonas, Jost B. Teo, Yik-Ying Mackey, David A. Oexle, Konrad Yoshimura, Nagahisa Paterson, Andrew D. Pfeiffer, Norbert Wong, Tien-Yin Baird, Paul N. Stambolian, Dwight Wilson, Joan E. Bailey Cheng, Ching-Yu Hammond, Christopher J. Klaver, Caroline C. W. Saw, Seang-Mei Rahi, Jugnoo S. Korobelnik, Jean-François Kemp, John P. Timpson, Nicholas J. Smith, George Davey Craig, Jamie E. Burdon, Kathryn P. Fogarty, Rhys D. Iyengar, Sudha K. Chew, Emily Janmahasatian, Sarayut Martin, Nicholas G. MacGregor, Stuart Xu, Liang Schache, Maria Nangia, Vinay Panda-Jonas, Songhomitra Wright, Alan F. Fondran, Jeremy R. Lass, Jonathan H. Feng, Sheng Zhao, Jing Hua Khaw, Kay-Tee Wareham, Nick J. Rantanen, Taina Kaprio, Jaakko Pang, Chi Pui Chen, Li Jia Tam, Pancy O. Jhanji, Vishal Young, Alvin L. Döring, Angela Raffel, Leslie J. Cotch, Mary-Frances Li, Xiaohui Yip, Shea Ping Yap, Maurice K.H. Biino, Ginevra Vaccargiu, Simona Fossarello, Maurizio Fleck, Brian Yazar, Seyhan Tideman, Jan Willem L. Tedja, Milly Deangelis, Margaret M. Morrison, Margaux Farrer, Lindsay Zhou, Xiangtian Chen, Wei Mizuki, Nobuhisa Meguro, Akira Mäkelä, Kari Matti |
| author_facet | Fan, Qiao Verhoeven, Virginie J. M. Wojciechowski, Robert Barathi, Veluchamy A. Hysi, Pirro G. Guggenheim, Jeremy A. Höhn, René Vitart, Veronique Khawaja, Anthony P. Yamashiro, Kenji Hosseini, S Mohsen Lehtimäki, Terho Lu, Yi Haller, Toomas Xie, Jing Delcourt, Cécile Pirastu, Mario Wedenoja, Juho Gharahkhani, Puya Venturini, Cristina Miyake, Masahiro Hewitt, Alex W. Guo, Xiaobo Mazur, Johanna Huffman, Jenifer E. Williams, Katie M. Polasek, Ozren Campbell, Harry Rudan, Igor Vatavuk, Zoran Wilson, James F. Joshi, Peter K. McMahon, George St Pourcain, Beate Evans, David M. Simpson, Claire L. Schwantes-An, Tae-Hwi Igo, Robert P. Mirshahi, Alireza Cougnard-Gregoire, Audrey Bellenguez, Céline Blettner, Maria Raitakari, Olli Kähönen, Mika Seppala, Ilkka Zeller, Tanja Meitinger, Thomas Ried, Janina S. Gieger, Christian Portas, Laura van Leeuwen, Elisabeth M. Amin, Najaf Uitterlinden, André G. Rivadeneira, Fernando Hofman, Albert Vingerling, Johannes R. Wang, Ya Xing Wang, Xu Tai-Hui Boh, Eileen Ikram, M. Kamran Sabanayagam, Charumathi Gupta, Preeti Tan, Vincent Zhou, Lei Ho, Candice E. H. Lim, Wan'e Beuerman, Roger W. Siantar, Rosalynn Tai, E-Shyong Vithana, Eranga Mihailov, Evelin Khor, Chiea-Chuen Hayward, Caroline Luben, Robert N. Foster, Paul J. Klein, Barbara E. K. Klein, Ronald Wong, Hoi-Suen Mitchell, Paul Metspalu, Andres Aung, Tin Young, Terri L. He, Mingguang Pärssinen, Olavi van Duijn, Cornelia M. Jin Wang, Jie Williams, Cathy Jonas, Jost B. Teo, Yik-Ying Mackey, David A. Oexle, Konrad Yoshimura, Nagahisa Paterson, Andrew D. Pfeiffer, Norbert Wong, Tien-Yin Baird, Paul N. Stambolian, Dwight Wilson, Joan E. Bailey Cheng, Ching-Yu Hammond, Christopher J. Klaver, Caroline C. W. Saw, Seang-Mei Rahi, Jugnoo S. Korobelnik, Jean-François Kemp, John P. Timpson, Nicholas J. Smith, George Davey Craig, Jamie E. Burdon, Kathryn P. Fogarty, Rhys D. Iyengar, Sudha K. Chew, Emily Janmahasatian, Sarayut Martin, Nicholas G. MacGregor, Stuart Xu, Liang Schache, Maria Nangia, Vinay Panda-Jonas, Songhomitra Wright, Alan F. Fondran, Jeremy R. Lass, Jonathan H. Feng, Sheng Zhao, Jing Hua Khaw, Kay-Tee Wareham, Nick J. Rantanen, Taina Kaprio, Jaakko Pang, Chi Pui Chen, Li Jia Tam, Pancy O. Jhanji, Vishal Young, Alvin L. Döring, Angela Raffel, Leslie J. Cotch, Mary-Frances Li, Xiaohui Yip, Shea Ping Yap, Maurice K.H. Biino, Ginevra Vaccargiu, Simona Fossarello, Maurizio Fleck, Brian Yazar, Seyhan Tideman, Jan Willem L. Tedja, Milly Deangelis, Margaret M. Morrison, Margaux Farrer, Lindsay Zhou, Xiangtian Chen, Wei Mizuki, Nobuhisa Meguro, Akira Mäkelä, Kari Matti |
| author_sort | Fan, Qiao |
| collection | PubMed |
| description | Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main effects and SNP × education interaction effects on refractive error in 40,036 adults from 25 studies of European ancestry and 10,315 adults from 9 studies of Asian ancestry. In European ancestry individuals, we identify six novel loci (FAM150B-ACP1, LINC00340, FBN1, DIS3L-MAP2K1, ARID2-SNAT1 and SLC14A2) associated with refractive error. In Asian populations, three genome-wide significant loci AREG, GABRR1 and PDE10A also exhibit strong interactions with education (P<8.5 × 10(−5)), whereas the interactions are less evident in Europeans. The discovery of these loci represents an important advance in understanding how gene and environment interactions contribute to the heterogeneity of myopia. |
| format | Online Article Text |
| id | pubmed-4820539 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-48205392016-04-17 Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error Fan, Qiao Verhoeven, Virginie J. M. Wojciechowski, Robert Barathi, Veluchamy A. Hysi, Pirro G. Guggenheim, Jeremy A. Höhn, René Vitart, Veronique Khawaja, Anthony P. Yamashiro, Kenji Hosseini, S Mohsen Lehtimäki, Terho Lu, Yi Haller, Toomas Xie, Jing Delcourt, Cécile Pirastu, Mario Wedenoja, Juho Gharahkhani, Puya Venturini, Cristina Miyake, Masahiro Hewitt, Alex W. Guo, Xiaobo Mazur, Johanna Huffman, Jenifer E. Williams, Katie M. Polasek, Ozren Campbell, Harry Rudan, Igor Vatavuk, Zoran Wilson, James F. Joshi, Peter K. McMahon, George St Pourcain, Beate Evans, David M. Simpson, Claire L. Schwantes-An, Tae-Hwi Igo, Robert P. Mirshahi, Alireza Cougnard-Gregoire, Audrey Bellenguez, Céline Blettner, Maria Raitakari, Olli Kähönen, Mika Seppala, Ilkka Zeller, Tanja Meitinger, Thomas Ried, Janina S. Gieger, Christian Portas, Laura van Leeuwen, Elisabeth M. Amin, Najaf Uitterlinden, André G. Rivadeneira, Fernando Hofman, Albert Vingerling, Johannes R. Wang, Ya Xing Wang, Xu Tai-Hui Boh, Eileen Ikram, M. Kamran Sabanayagam, Charumathi Gupta, Preeti Tan, Vincent Zhou, Lei Ho, Candice E. H. Lim, Wan'e Beuerman, Roger W. Siantar, Rosalynn Tai, E-Shyong Vithana, Eranga Mihailov, Evelin Khor, Chiea-Chuen Hayward, Caroline Luben, Robert N. Foster, Paul J. Klein, Barbara E. K. Klein, Ronald Wong, Hoi-Suen Mitchell, Paul Metspalu, Andres Aung, Tin Young, Terri L. He, Mingguang Pärssinen, Olavi van Duijn, Cornelia M. Jin Wang, Jie Williams, Cathy Jonas, Jost B. Teo, Yik-Ying Mackey, David A. Oexle, Konrad Yoshimura, Nagahisa Paterson, Andrew D. Pfeiffer, Norbert Wong, Tien-Yin Baird, Paul N. Stambolian, Dwight Wilson, Joan E. Bailey Cheng, Ching-Yu Hammond, Christopher J. Klaver, Caroline C. W. Saw, Seang-Mei Rahi, Jugnoo S. Korobelnik, Jean-François Kemp, John P. Timpson, Nicholas J. Smith, George Davey Craig, Jamie E. Burdon, Kathryn P. Fogarty, Rhys D. Iyengar, Sudha K. Chew, Emily Janmahasatian, Sarayut Martin, Nicholas G. MacGregor, Stuart Xu, Liang Schache, Maria Nangia, Vinay Panda-Jonas, Songhomitra Wright, Alan F. Fondran, Jeremy R. Lass, Jonathan H. Feng, Sheng Zhao, Jing Hua Khaw, Kay-Tee Wareham, Nick J. Rantanen, Taina Kaprio, Jaakko Pang, Chi Pui Chen, Li Jia Tam, Pancy O. Jhanji, Vishal Young, Alvin L. Döring, Angela Raffel, Leslie J. Cotch, Mary-Frances Li, Xiaohui Yip, Shea Ping Yap, Maurice K.H. Biino, Ginevra Vaccargiu, Simona Fossarello, Maurizio Fleck, Brian Yazar, Seyhan Tideman, Jan Willem L. Tedja, Milly Deangelis, Margaret M. Morrison, Margaux Farrer, Lindsay Zhou, Xiangtian Chen, Wei Mizuki, Nobuhisa Meguro, Akira Mäkelä, Kari Matti Nat Commun Article Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main effects and SNP × education interaction effects on refractive error in 40,036 adults from 25 studies of European ancestry and 10,315 adults from 9 studies of Asian ancestry. In European ancestry individuals, we identify six novel loci (FAM150B-ACP1, LINC00340, FBN1, DIS3L-MAP2K1, ARID2-SNAT1 and SLC14A2) associated with refractive error. In Asian populations, three genome-wide significant loci AREG, GABRR1 and PDE10A also exhibit strong interactions with education (P<8.5 × 10(−5)), whereas the interactions are less evident in Europeans. The discovery of these loci represents an important advance in understanding how gene and environment interactions contribute to the heterogeneity of myopia. Nature Publishing Group 2016-03-29 /pmc/articles/PMC4820539/ /pubmed/27020472 http://dx.doi.org/10.1038/ncomms11008 Text en Copyright © 2016, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| spellingShingle | Article Fan, Qiao Verhoeven, Virginie J. M. Wojciechowski, Robert Barathi, Veluchamy A. Hysi, Pirro G. Guggenheim, Jeremy A. Höhn, René Vitart, Veronique Khawaja, Anthony P. Yamashiro, Kenji Hosseini, S Mohsen Lehtimäki, Terho Lu, Yi Haller, Toomas Xie, Jing Delcourt, Cécile Pirastu, Mario Wedenoja, Juho Gharahkhani, Puya Venturini, Cristina Miyake, Masahiro Hewitt, Alex W. Guo, Xiaobo Mazur, Johanna Huffman, Jenifer E. Williams, Katie M. Polasek, Ozren Campbell, Harry Rudan, Igor Vatavuk, Zoran Wilson, James F. Joshi, Peter K. McMahon, George St Pourcain, Beate Evans, David M. Simpson, Claire L. Schwantes-An, Tae-Hwi Igo, Robert P. Mirshahi, Alireza Cougnard-Gregoire, Audrey Bellenguez, Céline Blettner, Maria Raitakari, Olli Kähönen, Mika Seppala, Ilkka Zeller, Tanja Meitinger, Thomas Ried, Janina S. Gieger, Christian Portas, Laura van Leeuwen, Elisabeth M. Amin, Najaf Uitterlinden, André G. Rivadeneira, Fernando Hofman, Albert Vingerling, Johannes R. Wang, Ya Xing Wang, Xu Tai-Hui Boh, Eileen Ikram, M. Kamran Sabanayagam, Charumathi Gupta, Preeti Tan, Vincent Zhou, Lei Ho, Candice E. H. Lim, Wan'e Beuerman, Roger W. Siantar, Rosalynn Tai, E-Shyong Vithana, Eranga Mihailov, Evelin Khor, Chiea-Chuen Hayward, Caroline Luben, Robert N. Foster, Paul J. Klein, Barbara E. K. Klein, Ronald Wong, Hoi-Suen Mitchell, Paul Metspalu, Andres Aung, Tin Young, Terri L. He, Mingguang Pärssinen, Olavi van Duijn, Cornelia M. Jin Wang, Jie Williams, Cathy Jonas, Jost B. Teo, Yik-Ying Mackey, David A. Oexle, Konrad Yoshimura, Nagahisa Paterson, Andrew D. Pfeiffer, Norbert Wong, Tien-Yin Baird, Paul N. Stambolian, Dwight Wilson, Joan E. Bailey Cheng, Ching-Yu Hammond, Christopher J. Klaver, Caroline C. W. Saw, Seang-Mei Rahi, Jugnoo S. Korobelnik, Jean-François Kemp, John P. Timpson, Nicholas J. Smith, George Davey Craig, Jamie E. Burdon, Kathryn P. Fogarty, Rhys D. Iyengar, Sudha K. Chew, Emily Janmahasatian, Sarayut Martin, Nicholas G. MacGregor, Stuart Xu, Liang Schache, Maria Nangia, Vinay Panda-Jonas, Songhomitra Wright, Alan F. Fondran, Jeremy R. Lass, Jonathan H. Feng, Sheng Zhao, Jing Hua Khaw, Kay-Tee Wareham, Nick J. Rantanen, Taina Kaprio, Jaakko Pang, Chi Pui Chen, Li Jia Tam, Pancy O. Jhanji, Vishal Young, Alvin L. Döring, Angela Raffel, Leslie J. Cotch, Mary-Frances Li, Xiaohui Yip, Shea Ping Yap, Maurice K.H. Biino, Ginevra Vaccargiu, Simona Fossarello, Maurizio Fleck, Brian Yazar, Seyhan Tideman, Jan Willem L. Tedja, Milly Deangelis, Margaret M. Morrison, Margaux Farrer, Lindsay Zhou, Xiangtian Chen, Wei Mizuki, Nobuhisa Meguro, Akira Mäkelä, Kari Matti Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title | Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title_full | Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title_fullStr | Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title_full_unstemmed | Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title_short | Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| title_sort | meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820539/ https://www.ncbi.nlm.nih.gov/pubmed/27020472 http://dx.doi.org/10.1038/ncomms11008 |
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metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT yoshimuranagahisa metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT patersonandrewd metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT pfeiffernorbert metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT wongtienyin metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT bairdpauln metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT stamboliandwight metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT wilsonjoanebailey metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT chengchingyu metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT hammondchristopherj metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT klavercarolinecw metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT sawseangmei metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT rahijugnoos metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT korobelnikjeanfrancois metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT kempjohnp metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT timpsonnicholasj metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT smithgeorgedavey metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT craigjamiee metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT burdonkathrynp metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT fogartyrhysd metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT iyengarsudhak metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT chewemily metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT janmahasatiansarayut metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT martinnicholasg metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT macgregorstuart metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT xuliang metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT schachemaria metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT nangiavinay metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT pandajonassonghomitra metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT wrightalanf metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT fondranjeremyr metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT lassjonathanh metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT fengsheng metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT zhaojinghua metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT khawkaytee metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT warehamnickj metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT rantanentaina metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT kapriojaakko metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT pangchipui metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT chenlijia metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT tampancyo metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT jhanjivishal metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT youngalvinl metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT doringangela metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT raffellesliej metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT cotchmaryfrances metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT lixiaohui metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT yipsheaping metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT yapmauricekh metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT biinoginevra metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT vaccargiusimona metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT fossarellomaurizio metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT fleckbrian metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT yazarseyhan metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT tidemanjanwilleml metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT tedjamilly metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT deangelismargaretm metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT morrisonmargaux metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT farrerlindsay metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT zhouxiangtian metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT chenwei metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT mizukinobuhisa metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT meguroakira metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror AT makelakarimatti metaanalysisofgeneenvironmentwideassociationscansaccountingforeducationlevelidentifiesadditionallociforrefractiveerror |