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Altered Sense of Humor in Dementia

Sense of humor is potentially relevant to social functioning in dementias, but has been little studied in these diseases. We designed a semi-structured informant questionnaire to assess humor behavior and preferences in patients with behavioral variant frontotemporal dementia (bvFTD; n = 15), semant...

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Autores principales: Clark, Camilla N., Nicholas, Jennifer M., Gordon, Elizabeth, Golden, Hannah L., Cohen, Miriam H., Woodward, Felix J., Macpherson, Kirsty, Slattery, Catherine F., Mummery, Catherine J., Schott, Jonathan M., Rohrer, Jonathan D., Warren, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820649/
https://www.ncbi.nlm.nih.gov/pubmed/26444779
http://dx.doi.org/10.3233/JAD-150413
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author Clark, Camilla N.
Nicholas, Jennifer M.
Gordon, Elizabeth
Golden, Hannah L.
Cohen, Miriam H.
Woodward, Felix J.
Macpherson, Kirsty
Slattery, Catherine F.
Mummery, Catherine J.
Schott, Jonathan M.
Rohrer, Jonathan D.
Warren, Jason D.
author_facet Clark, Camilla N.
Nicholas, Jennifer M.
Gordon, Elizabeth
Golden, Hannah L.
Cohen, Miriam H.
Woodward, Felix J.
Macpherson, Kirsty
Slattery, Catherine F.
Mummery, Catherine J.
Schott, Jonathan M.
Rohrer, Jonathan D.
Warren, Jason D.
author_sort Clark, Camilla N.
collection PubMed
description Sense of humor is potentially relevant to social functioning in dementias, but has been little studied in these diseases. We designed a semi-structured informant questionnaire to assess humor behavior and preferences in patients with behavioral variant frontotemporal dementia (bvFTD; n = 15), semantic dementia (SD; n = 7), progressive nonfluent aphasia (PNFA; n = 10), and Alzheimer’s disease (AD; n = 16) versus healthy age-matched individuals (n = 21). Altered (including frankly inappropriate) humor responses were significantly more frequent in bvFTD and SD (all patients) than PNFA or AD (around 40% of patients). All patient groups liked satirical and absurdist comedy significantly less than did healthy controls. This pattern was reported premorbidly for satirical comedy in bvFTD, PNFA, and AD. Liking for slapstick comedy did not differ between groups. Altered sense of humor is particularly salient in bvFTD and SD, but also frequent in AD and PNFA. Humor may be a sensitive probe of social cognitive impairment in dementia, with diagnostic, biomarker and social implications.
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spelling pubmed-48206492016-04-05 Altered Sense of Humor in Dementia Clark, Camilla N. Nicholas, Jennifer M. Gordon, Elizabeth Golden, Hannah L. Cohen, Miriam H. Woodward, Felix J. Macpherson, Kirsty Slattery, Catherine F. Mummery, Catherine J. Schott, Jonathan M. Rohrer, Jonathan D. Warren, Jason D. J Alzheimers Dis Research Article Sense of humor is potentially relevant to social functioning in dementias, but has been little studied in these diseases. We designed a semi-structured informant questionnaire to assess humor behavior and preferences in patients with behavioral variant frontotemporal dementia (bvFTD; n = 15), semantic dementia (SD; n = 7), progressive nonfluent aphasia (PNFA; n = 10), and Alzheimer’s disease (AD; n = 16) versus healthy age-matched individuals (n = 21). Altered (including frankly inappropriate) humor responses were significantly more frequent in bvFTD and SD (all patients) than PNFA or AD (around 40% of patients). All patient groups liked satirical and absurdist comedy significantly less than did healthy controls. This pattern was reported premorbidly for satirical comedy in bvFTD, PNFA, and AD. Liking for slapstick comedy did not differ between groups. Altered sense of humor is particularly salient in bvFTD and SD, but also frequent in AD and PNFA. Humor may be a sensitive probe of social cognitive impairment in dementia, with diagnostic, biomarker and social implications. IOS Press 2015-09-24 /pmc/articles/PMC4820649/ /pubmed/26444779 http://dx.doi.org/10.3233/JAD-150413 Text en IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Clark, Camilla N.
Nicholas, Jennifer M.
Gordon, Elizabeth
Golden, Hannah L.
Cohen, Miriam H.
Woodward, Felix J.
Macpherson, Kirsty
Slattery, Catherine F.
Mummery, Catherine J.
Schott, Jonathan M.
Rohrer, Jonathan D.
Warren, Jason D.
Altered Sense of Humor in Dementia
title Altered Sense of Humor in Dementia
title_full Altered Sense of Humor in Dementia
title_fullStr Altered Sense of Humor in Dementia
title_full_unstemmed Altered Sense of Humor in Dementia
title_short Altered Sense of Humor in Dementia
title_sort altered sense of humor in dementia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820649/
https://www.ncbi.nlm.nih.gov/pubmed/26444779
http://dx.doi.org/10.3233/JAD-150413
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