Cargando…

Tracking TCRβ Sequence Clonotype Expansions during Antiviral Therapy Using High-Throughput Sequencing of the Hypervariable Region

To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses during chronic infection and antiviral therapy. Co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robinson, Mark W., Hughes, Joseph, Wilkie, Gavin S., Swann, Rachael, Barclay, Stephen T., Mills, Peter R., Patel, Arvind H., Thomson, Emma C., McLauchlan, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820669/ https://www.ncbi.nlm.nih.gov/pubmed/27092143 http://dx.doi.org/10.3389/fimmu.2016.00131

Ejemplares similares

Identifying and Tracking Low-Frequency Virus-Specific TCR Clonotypes Using High-Throughput Sequencing
por: Wolf, Kyle, et al.
Publicado: (2018)

Durable Expansion of TCR-δ Meta-Clonotypes After BCG Revaccination in Humans
por: James, Charlotte A., et al.
Publicado: (2022)

TCR Sequencing in Mouse Models of Allorecognition Unveils the Features of Directly and Indirectly Activated Clonotypes
por: Tereshchenko, Valeriy, et al.
Publicado: (2023)

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences
por: Gurun, Burcu, et al.
Publicado: (2023)

An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences
por: Gurun, Burcu, et al.
Publicado: (2023)

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes
por: Hill, Danika L., et al.
Publicado: (2019)

How many TCR clonotypes does a body maintain?
por: Lythe, Grant, et al.
Publicado: (2016)

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis
por: Rossetti, Maura, et al.
Publicado: (2017)

Deep TCR repertoire sequencing reveals relative change in peanut specific clonotype in subjects undergoing rush oral immunotherapy
por: Bégin, Philippe, et al.
Publicado: (2014)

GLUE: a flexible software system for virus sequence data
por: Singer, Joshua B., et al.
Publicado: (2018)

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes
por: Abbas, Hussein A., et al.
Publicado: (2021)

Next-Generation Sequencing Sheds Light on the Natural History of Hepatitis C Infection in Patients Who Fail Treatment
por: Abdelrahman, Tamer, et al.
Publicado: (2015)

TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines
por: Jordan, Kimberly R., et al.
Publicado: (2012)

Elevated interferon-stimulated gene transcription in peripheral blood mononuclear cells occurs in patients infected with genotype 1 but not genotype 3 hepatitis C virus
por: Robinson, M W, et al.
Publicado: (2015)

Precision immunophenotyping by high-throughput TCR sequencing in human glioma
por: Sims, Jennifer, et al.
Publicado: (2015)

Discriminating Clonotypes of Influenza A Virus Genes by Nanopore Sequencing
por: Cao, Ying, et al.
Publicado: (2021)

TCR meta-clonotypes for biomarker discovery with tcrdist3: identification of public, HLA-restricted SARS-CoV-2 associated TCR features
por: Mayer-Blackwell, Koshlan, et al.
Publicado: (2021)

Use of high throughput T cell receptor (TCR) DNA sequencing to characterize T cell infusion products and track clonal expansion in vivo
por: Strohl, Madeleine, et al.
Publicado: (2014)

Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection
por: Robinson, Mark W., et al.
Publicado: (2015)

Sequence and functional characterization of a public HIV-specific antibody clonotype
por: Murji, Amyn A., et al.
Publicado: (2021)

Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing
por: Lee, Edward S., et al.
Publicado: (2017)

A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires
por: Tanno, Hidetaka, et al.
Publicado: (2020)

Convergent antibody evolution and clonotype expansion following influenza virus vaccination
por: Forgacs, David, et al.
Publicado: (2021)

Sequence analysis of the hypervariable region in hmtp210 of Avibacterium paragallinarum
por: ARAYA-HIDALGO, Edward, et al.
Publicado: (2017)

Restricted TcR β chain CDR3 clonotype is associated with resolved acute hepatitis B subjects
por: Xiao, Dangsheng, et al.
Publicado: (2021)

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response
por: Merkenschlager, Julia, et al.
Publicado: (2016)

Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome
por: Caraballo Cortés, Kamila, et al.
Publicado: (2014)

T-cell clonotypes in cancer
por: thor Straten, Per, et al.
Publicado: (2004)

The complementarity-determining region sequences in IgY antivenom hypervariable regions
por: da Rocha, David Gitirana, et al.
Publicado: (2017)

High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire
por: Hou, Xianliang, et al.
Publicado: (2016)

Profiling of the TCRβ repertoire in non-model species using high-throughput sequencing
por: Migalska, Magdalena, et al.
Publicado: (2018)

High frequency CD8+PD-1+ TCR clonotypes isolated from fresh melanomas display anti-tumor activity
por: Anna, Pasetto, et al.
Publicado: (2015)

Analysis of mixtures using next generation sequencing of mitochondrial DNA hypervariable regions
por: Kim, Hanna, et al.
Publicado: (2015)

Sequence polymorphism data of the hypervariable regions of mitochondrial DNA in the Yadav population of Haryana
por: Verma, Kapil, et al.
Publicado: (2018)

Single-Cell RNA Sequencing for the Detection of Clonotypic V(D)J Rearrangements in Multiple Myeloma
por: Matera, Antonio, et al.
Publicado: (2022)

Read the clonotype: Next-generation sequencing-based lymphocyte clonality analysis and perspectives for application in pathology
por: Groenen, Patricia J. T. A., et al.
Publicado: (2023)

GagCM9-Specific CD8(+) T Cells Expressing Limited Public TCR Clonotypes Do Not Suppress SIV Replication In Vivo
por: Vojnov, Lara, et al.
Publicado: (2011)

The complex and specific pMHC interactions with diverse HIV-1 TCR clonotypes reveal a structural basis for alterations in CTL function
por: Xia, Zhen, et al.
Publicado: (2014)

High‐throughput single‐cell sequencing of paired TCRα and TCRβ genes for the direct expression‐cloning and functional analysis of murine T‐cell receptors
por: Ludwig, Julia, et al.
Publicado: (2019)

Analysis of the Bacterial Communities in Two Liquors of Soy Sauce Aroma as Revealed by High-Throughput Sequencing of the 16S rRNA V4 Hypervariable Region
por: Tang, Jing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7rsgoi0kfqkei2kgbpq83cf4rf