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Enterovirus 71 induces dsRNA/PKR-dependent cytoplasmic redistribution of GRP78/BiP to promote viral replication

GRP78/BiP is an endoplasmic reticulum (ER) chaperone protein with the important function of maintaining ER homeostasis, and the overexpression of GRP78/BiP alleviates ER stress. Our previous studies showed that infection with enterovirus 71 (EV71), a (+)RNA picornavirus, induced GRP78/BiP upregulati...

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Detalles Bibliográficos
Autores principales:	Jheng, Jia-Rong, Wang, Shin-Chyang, Jheng, Chao-Rih, Horng, Jim-Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820672/ https://www.ncbi.nlm.nih.gov/pubmed/27004760 http://dx.doi.org/10.1038/emi.2016.20

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