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Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression

Sex-determining region Y box 6 (SOX6) has been described as a tumor-suppressor gene in several cancers. Our previous work has suggested that SOX6 upregulated p21(Waf1/Cip1)(p21) expression in a p53-dependent manner; however, the underlying mechanism has remained elusive. In this study, we confirmed...

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Detalles Bibliográficos
Autores principales:	Wang, J, Ding, S, Duan, Z, Xie, Q, Zhang, T, Zhang, X, Wang, Y, Chen, X, Zhuang, H, Lu, F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820682/ https://www.ncbi.nlm.nih.gov/pubmed/26119940 http://dx.doi.org/10.1038/onc.2015.234

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