Reverse genetics in high throughput: rapid generation of complete negative strand RNA virus cDNA clones and recombinant viruses thereof

Reverse genetics approaches are indispensable tools for proof of concepts in virus replication and pathogenesis. For negative strand RNA viruses (NSVs) the limited number of infectious cDNA clones represents a bottleneck as clones are often generated from cell culture adapted or attenuated viruses,...

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Detalles Bibliográficos
Autores principales: Nolden, T., Pfaff, F., Nemitz, S., Freuling, C. M., Höper, D., Müller, T., Finke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820695/
https://www.ncbi.nlm.nih.gov/pubmed/27046474
http://dx.doi.org/10.1038/srep23887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820695/
https://www.ncbi.nlm.nih.gov/pubmed/27046474
http://dx.doi.org/10.1038/srep23887

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