Tetrahydroanthraquinone Derivative (±)-4-Deoxyaustrocortilutein Induces Cell Cycle Arrest and Apoptosis in Melanoma Cells via Upregulation of p21 and p53 and Downregulation of NF-kappaB

Background: Malignant melanoma is an aggressive type of skin cancer with high risk for metastasis and chemoresistance. Disruption of tightly regulated processes such as cell cycle, cell adhesion, cell differentiation and cell death are predominant in melanoma development. So far, conventional treatm...

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Detalles Bibliográficos
Autores principales: Genov, Miroslav, Kreiseder, Birgit, Nagl, Michael, Drucker, Elisabeth, Wiederstein, Martina, Muellauer, Barbara, Krebs, Julia, Grohmann, Teresa, Pretsch, Dagmar, Baumann, Karl, Bacher, Markus, Pretsch, Alexander, Wiesner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820732/
https://www.ncbi.nlm.nih.gov/pubmed/27053954
http://dx.doi.org/10.7150/jca.13614

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