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A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications
Hyperspectral imaging has proven significance in bio-imaging applications and it has the ability to capture up to several hundred images of different wavelengths offering relevant spectral signatures. To use hyperspectral imaging for in vivo monitoring and diagnosis of the internal body cavities, a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820774/ https://www.ncbi.nlm.nih.gov/pubmed/27044607 http://dx.doi.org/10.1038/srep24044 |
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author | Lim, Hoong-Ta Murukeshan, Vadakke Matham |
author_facet | Lim, Hoong-Ta Murukeshan, Vadakke Matham |
author_sort | Lim, Hoong-Ta |
collection | PubMed |
description | Hyperspectral imaging has proven significance in bio-imaging applications and it has the ability to capture up to several hundred images of different wavelengths offering relevant spectral signatures. To use hyperspectral imaging for in vivo monitoring and diagnosis of the internal body cavities, a snapshot hyperspectral video-endoscope is required. However, such reported systems provide only about 50 wavelengths. We have developed a four-dimensional snapshot hyperspectral video-endoscope with a spectral range of 400–1000 nm, which can detect 756 wavelengths for imaging, significantly more than such systems. Capturing the three-dimensional datacube sequentially gives the fourth dimension. All these are achieved through a flexible two-dimensional to one-dimensional fiber bundle. The potential of this custom designed and fabricated compact biomedical probe is demonstrated by imaging phantom tissue samples in reflectance and fluorescence imaging modalities. It is envisaged that this novel concept and developed probe will contribute significantly towards diagnostic in vivo biomedical imaging in the near future. |
format | Online Article Text |
id | pubmed-4820774 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48207742016-04-06 A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications Lim, Hoong-Ta Murukeshan, Vadakke Matham Sci Rep Article Hyperspectral imaging has proven significance in bio-imaging applications and it has the ability to capture up to several hundred images of different wavelengths offering relevant spectral signatures. To use hyperspectral imaging for in vivo monitoring and diagnosis of the internal body cavities, a snapshot hyperspectral video-endoscope is required. However, such reported systems provide only about 50 wavelengths. We have developed a four-dimensional snapshot hyperspectral video-endoscope with a spectral range of 400–1000 nm, which can detect 756 wavelengths for imaging, significantly more than such systems. Capturing the three-dimensional datacube sequentially gives the fourth dimension. All these are achieved through a flexible two-dimensional to one-dimensional fiber bundle. The potential of this custom designed and fabricated compact biomedical probe is demonstrated by imaging phantom tissue samples in reflectance and fluorescence imaging modalities. It is envisaged that this novel concept and developed probe will contribute significantly towards diagnostic in vivo biomedical imaging in the near future. Nature Publishing Group 2016-04-05 /pmc/articles/PMC4820774/ /pubmed/27044607 http://dx.doi.org/10.1038/srep24044 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Lim, Hoong-Ta Murukeshan, Vadakke Matham A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title | A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title_full | A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title_fullStr | A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title_full_unstemmed | A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title_short | A four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
title_sort | four-dimensional snapshot hyperspectral video-endoscope for bio-imaging applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820774/ https://www.ncbi.nlm.nih.gov/pubmed/27044607 http://dx.doi.org/10.1038/srep24044 |
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