Cleaning out the Litterbox of Proteomic Scientists’ Favorite Pet: Optimized Data Analysis Avoiding Trypsin Artifacts

[Image: see text] Chemically modified trypsin is a standard reagent in proteomics experiments but is usually not considered in database searches. Modification of trypsin is supposed to protect the protease against autolysis and the resulting loss of activity. Here, we show that modified trypsin is s...

Descripción completa

Detalles Bibliográficos
Autores principales: Schittmayer, Matthias, Fritz, Katarina, Liesinger, Laura, Griss, Johannes, Birner-Gruenberger, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820788/
https://www.ncbi.nlm.nih.gov/pubmed/26938934
http://dx.doi.org/10.1021/acs.jproteome.5b01105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820788/
https://www.ncbi.nlm.nih.gov/pubmed/26938934
http://dx.doi.org/10.1021/acs.jproteome.5b01105

Ejemplares similares