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Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome123
Altered metabolism is an important feature of many epileptic syndromes but has not been reported in Dravet syndrome (DS), a catastrophic childhood epilepsy associated with mutations in a voltage-activated sodium channel, Nav1.1 (SCN1A). To address this, we developed novel methodology to assess real-...
Autores principales: | Kumar, Maneesh G., Rowley, Shane, Fulton, Ruth, Dinday, Matthew T., Baraban, Scott C., Patel, Manisha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820792/ https://www.ncbi.nlm.nih.gov/pubmed/27066534 http://dx.doi.org/10.1523/ENEURO.0008-16.2016 |
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