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Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting

Post-translational modifications (PTMs) of receptor tyrosine kinases (RTKs) at the plasma membrane (PM) determine the signal transduction efficacy alone and in combination. However, current approaches to identify PTMs provide ensemble results, inherently overlooking combinatorial PTMs in a single po...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Lock, Kim, Daehyung, Lee, Seongsil, Kim, Su-Jeong, Noh, Jung Eun, Kim, Joung-Hun, Chae, Young Chan, Lee, Jong-Bong, Ryu, Sung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820850/
https://www.ncbi.nlm.nih.gov/pubmed/27009355
http://dx.doi.org/10.1038/ncomms11107