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Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting
Post-translational modifications (PTMs) of receptor tyrosine kinases (RTKs) at the plasma membrane (PM) determine the signal transduction efficacy alone and in combination. However, current approaches to identify PTMs provide ensemble results, inherently overlooking combinatorial PTMs in a single po...
Autores principales: | Kim, Kyung Lock, Kim, Daehyung, Lee, Seongsil, Kim, Su-Jeong, Noh, Jung Eun, Kim, Joung-Hun, Chae, Young Chan, Lee, Jong-Bong, Ryu, Sung Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820850/ https://www.ncbi.nlm.nih.gov/pubmed/27009355 http://dx.doi.org/10.1038/ncomms11107 |
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