Serine/threonine kinases 31(STK31) may be a novel cellular target gene for the HPV16 oncogene E7 with potential as a DNA hypomethylation biomarker in cervical cancer

BACKGROUND: Cervical cancer (CC) is a leading cause of mortality in females, especially in developing countries. The two viral oncoproteins E6 and E7 mediate the oncogenic activities of high-risk human papillomavirus (hrHPV), and hrHPV, especially HPV16 or/and HPV18 (HPV16/18) play critical roles in...

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Detalles Bibliográficos
Autores principales: Yin, Fu-Fen, Wang, Ning, Bi, Xiao-Ning, Yu, Xiao, Xu, Xiao-Hui, Wang, You-Lin, Zhao, Cheng-Quan, Luo, Bing, Wang, Yan-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820863/
https://www.ncbi.nlm.nih.gov/pubmed/27044426
http://dx.doi.org/10.1186/s12985-016-0515-5

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