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Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial

BACKGROUND: Because type 2 diabetes mellitus is associated strongly with an increased risk of cardiovascular diseases, the number of patients with diabetes with chronic heart failure is increasing steadily. However, clinical evidence of therapeutic strategies in such patients is still lacking. A rec...

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Detalles Bibliográficos
Autores principales: Tanaka, Atsushi, Inoue, Teruo, Kitakaze, Masafumi, Oyama, Jun-ichi, Sata, Masataka, Taguchi, Isao, Shimizu, Wataru, Watada, Hirotaka, Tomiyama, Hirofumi, Ako, Junya, Sakata, Yasushi, Anzai, Toshihisa, Uematsu, Masaaki, Suzuki, Makoto, Eguchi, Kazuo, Yamashina, Akira, Saito, Yoshihiko, Sato, Yasunori, Ueda, Shinichiro, Murohara, Toyoaki, Node, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820875/
https://www.ncbi.nlm.nih.gov/pubmed/27044332
http://dx.doi.org/10.1186/s12933-016-0381-x