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Population pharmacokinetic analysis and dosing regimen optimization of penicillin G in patients with infective endocarditis

BACKGROUND: This study was designed to evaluate the population pharmacokinetics (popPK) of penicillin G in patients with infective endocarditis and establish a dosage regimen based on pharmacokinetic data and clinical outcome. METHOD: Forty-six serum penicillin G samples from 25 individuals were ana...

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Detalles Bibliográficos
Autores principales:	Komatsu, Toshiaki, Inomata, Takayuki, Watanabe, Ichiro, Kobayashi, Masahiro, Kokubun, Hideya, Ako, Junya, Atsuda, Koichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820900/ https://www.ncbi.nlm.nih.gov/pubmed/27051524 http://dx.doi.org/10.1186/s40780-016-0043-x

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