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Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents
Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We investigate these networks in rodents using a two-interval timing task while recording LFPs in medial frontal cortex (MFC) or dorsomedial st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820903/ https://www.ncbi.nlm.nih.gov/pubmed/27092091 http://dx.doi.org/10.3389/fpsyg.2016.00459 |
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author | Emmons, Eric B. Ruggiero, Rafael N. Kelley, Ryan M. Parker, Krystal L. Narayanan, Nandakumar S. |
author_facet | Emmons, Eric B. Ruggiero, Rafael N. Kelley, Ryan M. Parker, Krystal L. Narayanan, Nandakumar S. |
author_sort | Emmons, Eric B. |
collection | PubMed |
description | Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We investigate these networks in rodents using a two-interval timing task while recording LFPs in medial frontal cortex (MFC) or dorsomedial striatum. Consistent with prior work, we found cue-triggered delta (1–4 Hz) and theta activity (4–8 Hz) primarily in rodent MFC. We observed delta activity across temporal intervals in MFC and dorsomedial striatum. Rewarded responses were associated with increased delta activity in MFC. Activity in theta bands in MFC and delta bands in the striatum was linked with the timing of responses. These data suggest both delta and theta activity in frontostriatal networks are modulated during interval timing and that activity in these bands may be involved in the temporal control of action. |
format | Online Article Text |
id | pubmed-4820903 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48209032016-04-18 Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents Emmons, Eric B. Ruggiero, Rafael N. Kelley, Ryan M. Parker, Krystal L. Narayanan, Nandakumar S. Front Psychol Psychology Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We investigate these networks in rodents using a two-interval timing task while recording LFPs in medial frontal cortex (MFC) or dorsomedial striatum. Consistent with prior work, we found cue-triggered delta (1–4 Hz) and theta activity (4–8 Hz) primarily in rodent MFC. We observed delta activity across temporal intervals in MFC and dorsomedial striatum. Rewarded responses were associated with increased delta activity in MFC. Activity in theta bands in MFC and delta bands in the striatum was linked with the timing of responses. These data suggest both delta and theta activity in frontostriatal networks are modulated during interval timing and that activity in these bands may be involved in the temporal control of action. Frontiers Media S.A. 2016-04-05 /pmc/articles/PMC4820903/ /pubmed/27092091 http://dx.doi.org/10.3389/fpsyg.2016.00459 Text en Copyright © 2016 Emmons, Ruggiero, Kelley, Parker and Narayanan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychology Emmons, Eric B. Ruggiero, Rafael N. Kelley, Ryan M. Parker, Krystal L. Narayanan, Nandakumar S. Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title | Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title_full | Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title_fullStr | Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title_full_unstemmed | Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title_short | Corticostriatal Field Potentials Are Modulated at Delta and Theta Frequencies during Interval-Timing Task in Rodents |
title_sort | corticostriatal field potentials are modulated at delta and theta frequencies during interval-timing task in rodents |
topic | Psychology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820903/ https://www.ncbi.nlm.nih.gov/pubmed/27092091 http://dx.doi.org/10.3389/fpsyg.2016.00459 |
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