Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

TAF4 (TATA-binding protein-associated factor 4) and its paralogue TAF4b are components of the TFIID core module. We inactivated the murine Taf4a gene to address Taf4 function during embryogenesis. Here we show that Taf4a(−/−) embryos survive until E9.5 where primary germ layers and many embryonic st...

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Detalles Bibliográficos
Autores principales: Langer, Diana, Martianov, Igor, Alpern, Daniel, Rhinn, Muriel, Keime, Céline, Dollé, Pascal, Mengus, Gabrielle, Davidson, Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820908/
https://www.ncbi.nlm.nih.gov/pubmed/27026076
http://dx.doi.org/10.1038/ncomms11063

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