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Colitis susceptibility in p47(phox−/−) mice is mediated by the microbiome

BACKGROUND: Chronic granulomatous disease (CGD) is caused by defects in nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) complex subunits (gp91(phox) (a.k.a. Nox2), p47(phox), p67(phox), p22(phox), p40(phox)) leading to reduced phagocyte-derived reactive oxygen species production. Almost...

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Detalles Bibliográficos
Autores principales:	Falcone, E. Liana, Abusleme, Loreto, Swamydas, Muthulekha, Lionakis, Michail S., Ding, Li, Hsu, Amy P., Zelazny, Adrian M., Moutsopoulos, Niki M., Kuhns, Douglas B., Deming, Clay, Quiñones, Mariam, Segre, Julia A., Bryant, Clare E., Holland, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820915/ https://www.ncbi.nlm.nih.gov/pubmed/27044504 http://dx.doi.org/10.1186/s40168-016-0159-0

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