TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

BACKGROUND: Recent genome-wide association studies revealed TREM2 rs75932628-T variant to be associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. However, the role that TREM2 plays in sporadic AD is largely unknown. Our aim was to assess messenger RNA (mRNA) expression leve...

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Detalles Bibliográficos
Autores principales: Celarain, Naiara, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Larumbe, Rosa, Pulido, Laura, Echavarri, Carmen, Mendioroz, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820985/
https://www.ncbi.nlm.nih.gov/pubmed/27051467
http://dx.doi.org/10.1186/s13148-016-0202-9

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