Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location

Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis challenging. Although it mostly originates in the stomach, several other sites of origin have been reported. We report a case of HAC originating in...

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Autores principales: Ogbonna, Onyekachi Henry, Sakruti, Susmita, Sulieman, Maha, Ali, Ahmed, Shokrani, Babak, Oneal, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Published online: March, 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821151/
https://www.ncbi.nlm.nih.gov/pubmed/27064217
http://dx.doi.org/10.1159/000444746
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author Ogbonna, Onyekachi Henry
Sakruti, Susmita
Sulieman, Maha
Ali, Ahmed
Shokrani, Babak
Oneal, Patricia
author_facet Ogbonna, Onyekachi Henry
Sakruti, Susmita
Sulieman, Maha
Ali, Ahmed
Shokrani, Babak
Oneal, Patricia
author_sort Ogbonna, Onyekachi Henry
collection PubMed
description Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis challenging. Although it mostly originates in the stomach, several other sites of origin have been reported. We report a case of HAC originating in the duodenum, a very unusual location. We also discuss an approach to the diagnosis of HAC using morphological and immunohistochemical features, and explore possible therapeutic options.
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spelling pubmed-48211512016-04-08 Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location Ogbonna, Onyekachi Henry Sakruti, Susmita Sulieman, Maha Ali, Ahmed Shokrani, Babak Oneal, Patricia Case Rep Oncol Published online: March, 2016 Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis challenging. Although it mostly originates in the stomach, several other sites of origin have been reported. We report a case of HAC originating in the duodenum, a very unusual location. We also discuss an approach to the diagnosis of HAC using morphological and immunohistochemical features, and explore possible therapeutic options. S. Karger AG 2016-03-12 /pmc/articles/PMC4821151/ /pubmed/27064217 http://dx.doi.org/10.1159/000444746 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Published online: March, 2016
Ogbonna, Onyekachi Henry
Sakruti, Susmita
Sulieman, Maha
Ali, Ahmed
Shokrani, Babak
Oneal, Patricia
Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title_full Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title_fullStr Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title_full_unstemmed Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title_short Hepatoid Adenocarcinoma of the Duodenum: An Unusual Location
title_sort hepatoid adenocarcinoma of the duodenum: an unusual location
topic Published online: March, 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821151/
https://www.ncbi.nlm.nih.gov/pubmed/27064217
http://dx.doi.org/10.1159/000444746
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