Two Cases of Hypophosphatemia with Increased Renal Phosphate Excretion in Legionella Pneumonia

We encountered 2 cases of hypophosphatemia due to Legionella pneumonia. Both cases showed increased urinary phosphate excretion and renal tubular dysfunction, which ameliorated with recovery from Legionella pneumonia. Serum fibroblast growth factor-23 level was suppressed, whereas serum 1,25(OH)(2)...

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Detalles Bibliográficos
Autores principales: Watanabe, Shuhei, Kono, Keiji, Fujii, Hideki, Nakai, Kentaro, Goto, Shunsuke, Nishi, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Published online: March, 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821156/
https://www.ncbi.nlm.nih.gov/pubmed/27066493
http://dx.doi.org/10.1159/000444875
Descripción
Sumario:We encountered 2 cases of hypophosphatemia due to Legionella pneumonia. Both cases showed increased urinary phosphate excretion and renal tubular dysfunction, which ameliorated with recovery from Legionella pneumonia. Serum fibroblast growth factor-23 level was suppressed, whereas serum 1,25(OH)(2) vitamin D and parathyroid hormone levels were normal. Delayed elevation of serum 1,25(OH)(2) vitamin D levels was observed with improvement in renal tubular function. These findings suggested hypophosphatemia might be mediated by renal tubular dysfunction.

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