Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2

Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2. Here, we show that a novel phosphorylation of fission yeast Gad8 (AGC kinase) on the evolutionarily conserved threonine 6 (Thr6) preven...

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Detalles Bibliográficos
Autores principales: Du, Wei, Forte, Gabriella M., Smith, Duncan, Petersen, Janni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821236/
https://www.ncbi.nlm.nih.gov/pubmed/26935949
http://dx.doi.org/10.1098/rsob.150189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821236/
https://www.ncbi.nlm.nih.gov/pubmed/26935949
http://dx.doi.org/10.1098/rsob.150189

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