Immunomodulatory effect of macrolides: At what cost?

We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appea...

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Detalles Bibliográficos
Autores principales: Kipourou, Maria, Manika, Katerina, Papavasileiou, Apostolos, Pitsiou, Georgia, Lada, Martha, Ntinapogias, Evangelos, Kioumis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821334/
https://www.ncbi.nlm.nih.gov/pubmed/27222784
http://dx.doi.org/10.1016/j.rmcr.2016.01.004
Descripción
Sumario:We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appealing for non- CF bronchiectasis patients, hiding a high risk for resistance emergence.

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