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Mutational probing of protein aggregates to design aggregation‐resistant proteins
Characterization of amorphous protein aggregates may offer insights into the process of aggregation. Eleven single amino acid mutants of lipase (LipA of Bacillus subtilis) were subjected to temperature‐induced aggregation, and the resultant aggregates were characterized for recovery of activity in t...
Autores principales: | Kamal, Mohamad Zahid, Kumar, Virender, Satyamurthi, Kundarapu, Das, Kushal Kumar, Rao, Nalam Madhusudhana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821347/ https://www.ncbi.nlm.nih.gov/pubmed/27239434 http://dx.doi.org/10.1002/2211-5463.12003 |
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