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mTOR inhibition by rapamycin increases ceramide synthesis by promoting transforming growth factor‐β1/Smad signaling in the skin

Although mammalian target of rapamycin (mTOR) mediates a wide variety of biological functions, little information is available on the effect of mTOR on the functions of skin cells. In this study, we investigated effects of mTOR inhibition by rapamycin on ceramide synthesis in the skin of rats and hu...

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Detalles Bibliográficos
Autores principales:	Yamane, Takumi, Muramatsu, Aimi, Yoshino, Sawako, Matsui, Sho, Shimura, Mari, Tsujii, Yoshimasa, Iwatsuki, Ken, Kobayashi‐Hattori, Kazuo, Oishi, Yuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821357/ https://www.ncbi.nlm.nih.gov/pubmed/27239444 http://dx.doi.org/10.1002/2211-5463.12039

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