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Reduction in Serum Uric Acid May Be Related to Methotrexate Efficacy in Early Rheumatoid Arthritis: Data from the Canadian Early Arthritis Cohort (CATCH)

OBJECTIVES: The mechanism of action of methotrexate in rheumatoid arthritis (RA) is complex. It may increase adenosine levels by blocking its conversion to uric acid (UA). This study was done to determine if methotrexate lowers UA in early RA (ERA). METHODS: Data were obtained from Canadian Early Ar...

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Detalles Bibliográficos
Autores principales:	Lee, Jason J., Bykerk, Vivian P., Dresser, George K., Boire, Gilles, Haraoui, Boulos, Hitchon, Carol, Thorne, Carter, Tin, Diane, Jamal, Shahin, Keystone, Edward C., Pope, Janet E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821431/ https://www.ncbi.nlm.nih.gov/pubmed/27081318 http://dx.doi.org/10.4137/CMAMD.S38092

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