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R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice

The R-spondin family of proteins has recently been described as secreted enhancers of β-catenin activation through the canonical Wnt signaling pathway. We previously reported that Rspo2 is a major determinant of susceptibility to Citrobacter rodentium-mediated colitis in mice and recent genome-wide...

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Detalles Bibliográficos
Autores principales: Kang, Eugene, Yousefi, Mitra, Gruenheid, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821485/
https://www.ncbi.nlm.nih.gov/pubmed/27046199
http://dx.doi.org/10.1371/journal.pone.0152859