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Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity

PURPOSE: To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE). METHODS: Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8...

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Autores principales: Kaido, Minako, Toda, Ikuko, Oobayashi, Tomoo, Kawashima, Motoko, Katada, Yusaku, Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821556/
https://www.ncbi.nlm.nih.gov/pubmed/27045760
http://dx.doi.org/10.1371/journal.pone.0152936
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author Kaido, Minako
Toda, Ikuko
Oobayashi, Tomoo
Kawashima, Motoko
Katada, Yusaku
Tsubota, Kazuo
author_facet Kaido, Minako
Toda, Ikuko
Oobayashi, Tomoo
Kawashima, Motoko
Katada, Yusaku
Tsubota, Kazuo
author_sort Kaido, Minako
collection PubMed
description PURPOSE: To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE). METHODS: Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20–49 years) underwent functional visual acuity (VA) examinations with and without wearing eyeglasses with 50% blue light blocked lenses. The functional VA parameters were starting VA, functional VA, and visual maintenance ratio. RESULTS: The baseline mean values (logarithm of the minimum angle of resolution, logMAR) of functional VA and the visual maintenance ratio were significantly worse in the DE patients than in the controls (P < 0.05), while no significant difference was observed in the baseline starting VA (P > 0.05). The DE patients had significant improvement in mean functional VA and visual maintenance ratio while wearing the glasses (P < 0.05), while there were no significant changes with and without the glasses in the control group (P > 0.05), CONCLUSIONS: Protecting the eyes from short-wavelength blue light may help to ameliorate visual impairment associated with tear instability in patients with DE. This finding represents a new concept, which is that the blue light exposure might be harmful to visual function in patients with short BUT DE.
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spelling pubmed-48215562016-04-22 Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity Kaido, Minako Toda, Ikuko Oobayashi, Tomoo Kawashima, Motoko Katada, Yusaku Tsubota, Kazuo PLoS One Research Article PURPOSE: To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE). METHODS: Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20–49 years) underwent functional visual acuity (VA) examinations with and without wearing eyeglasses with 50% blue light blocked lenses. The functional VA parameters were starting VA, functional VA, and visual maintenance ratio. RESULTS: The baseline mean values (logarithm of the minimum angle of resolution, logMAR) of functional VA and the visual maintenance ratio were significantly worse in the DE patients than in the controls (P < 0.05), while no significant difference was observed in the baseline starting VA (P > 0.05). The DE patients had significant improvement in mean functional VA and visual maintenance ratio while wearing the glasses (P < 0.05), while there were no significant changes with and without the glasses in the control group (P > 0.05), CONCLUSIONS: Protecting the eyes from short-wavelength blue light may help to ameliorate visual impairment associated with tear instability in patients with DE. This finding represents a new concept, which is that the blue light exposure might be harmful to visual function in patients with short BUT DE. Public Library of Science 2016-04-05 /pmc/articles/PMC4821556/ /pubmed/27045760 http://dx.doi.org/10.1371/journal.pone.0152936 Text en © 2016 Kaido et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kaido, Minako
Toda, Ikuko
Oobayashi, Tomoo
Kawashima, Motoko
Katada, Yusaku
Tsubota, Kazuo
Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title_full Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title_fullStr Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title_full_unstemmed Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title_short Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
title_sort reducing short-wavelength blue light in dry eye patients with unstable tear film improves performance on tests of visual acuity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821556/
https://www.ncbi.nlm.nih.gov/pubmed/27045760
http://dx.doi.org/10.1371/journal.pone.0152936
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