Oxidative Deamination of Serum Albumins by (-)-Epigallocatechin-3-O-Gallate: A Potential Mechanism for the Formation of Innate Antigens by Antioxidants

(-)-Epigallocatechin-3-O-gallate (EGCG), the most abundant polyphenol in green tea, mediates the oxidative modification of proteins, generating protein carbonyls. However, the underlying molecular mechanism remains unclear. Here we analyzed the EGCG-derived intermediates generated upon incubation wi...

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Detalles Bibliográficos
Autores principales: Hatasa, Yukinori, Chikazawa, Miho, Furuhashi, Mai, Nakashima, Fumie, Shibata, Takahiro, Kondo, Tatsuhiko, Akagawa, Mitsugu, Hamagami, Hiroki, Tanaka, Hiroshi, Tachibana, Hirofumi, Uchida, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821561/
https://www.ncbi.nlm.nih.gov/pubmed/27046229
http://dx.doi.org/10.1371/journal.pone.0153002

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