Cargando…

Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1(tm1Fbg) (Lpd(-/-)) was documented. Upon further investigation, the Lpd(-/-) colony was found to be infected wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miller, Cassandra L., Muthupalani, Sureshkumar, Shen, Zeli, Drees, Frauke, Ge, Zhongming, Feng, Yan, Chen, Xiaowei, Gong, Guanyu, Nagar, Karan K., Wang, Timothy C., Gertler, Frank B., Fox, James G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821566/ https://www.ncbi.nlm.nih.gov/pubmed/27045955 http://dx.doi.org/10.1371/journal.pone.0152940

Ejemplares similares

Lamellipodin Is Important for Cell-to-Cell Spread and Actin-Based Motility in Listeria monocytogenes
por: Wang, Jiahui, et al.
Publicado: (2015)

Lamellipodin branches out
por: Short, Ben
Publicado: (2013)

Male-Dependent Promotion of Colitis in 129 Rag2(−/−) Mice Co-Infected with Helicobacter pylori and Helicobacter hepaticus
por: Ge, Zhongming, et al.
Publicado: (2020)

Natural Transmission of Helicobacter saguini Causes Multigenerational Inflammatory Bowel Disease in C57/129 IL-10(−/−) Mice
por: Mannion, Anthony, et al.
Publicado: (2020)

Myosin-X recruits lamellipodin to filopodia tips
por: Popović, Ana, et al.
Publicado: (2023)

Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo
por: Kiraly, Orsolya, et al.
Publicado: (2015)

Initiation and disassembly of filopodia tip complexes containing VASP and lamellipodin
por: Cheng, Karen W., et al.
Publicado: (2020)

Helicobacter pylori Infection Induces Anemia, Depletes Serum Iron Storage, and Alters Local Iron-Related and Adult Brain Gene Expression in Male INS-GAS Mice
por: Burns, Monika, et al.
Publicado: (2015)

Identification of a new strain of mouse kidney parvovirus associated with inclusion body nephropathy in immunocompromised laboratory mice
por: Ge, Zhongming, et al.
Publicado: (2020)

Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo
por: Law, Ah-Lai, et al.
Publicado: (2013)

Brain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice
por: Bodo, Cristian, et al.
Publicado: (2017)

Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE
por: Carmona, G, et al.
Publicado: (2016)

Helicobacter pylori-infected C57BL/6 mice with different gastrointestinal microbiota have contrasting gastric pathology, microbial and host immune responses
por: Ge, Zhongming, et al.
Publicado: (2018)

Lamellipodin-RICTOR Signaling Mediates Glioblastoma Cell Invasion and Radiosensitivity Downstream of EGFR
por: Moritz, Stefanie, et al.
Publicado: (2021)

Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori induced corpus mucous metaplasia
por: Muthupalani, Sureshkumar, et al.
Publicado: (2019)

IL-1β transgenic mouse model of inflammation driven esophageal and oral squamous cell carcinoma
por: Muthupalani, Sureshkumar, et al.
Publicado: (2023)

Persistent infection of rhesus monkeys with ‘Helicobacter macacae’ and its isolation from an animal with intestinal adenocarcinoma
por: Marini, Robert P., et al.
Publicado: (2010)

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis
por: Vehlow, Anne, et al.
Publicado: (2013)

An Analysis of the Role of the Indigenous Microbiota in Cholesterol Gallstone Pathogenesis
por: Fremont-Rahl, Jacqueline J., et al.
Publicado: (2013)

Helicobacter hepaticus Infection Promotes Hepatitis and Preneoplastic Foci in Farnesoid X Receptor (FXR) Deficient Mice
por: Swennes, Alton G., et al.
Publicado: (2014)

c-Abl, Lamellipodin, and Ena/VASP Proteins Cooperate in Dorsal Ruffling of Fibroblasts and Axonal Morphogenesis
por: Michael, Magdalene, et al.
Publicado: (2010)

Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments
por: Hansen, Scott D, et al.
Publicado: (2015)

Ganoderma lucidum Extract Reduces the Motility of Breast Cancer Cells Mediated by the RAC–Lamellipodin Axis
por: Acevedo-Díaz, Ariana, et al.
Publicado: (2019)

The Lamellipodin homologue MIG-10 is not essential for dorsal intercalation in the embryonic epidermis of the C. elegans embryo
por: Serre, Joel M., et al.
Publicado: (2022)

Nephrin Regulates Lamellipodia Formation by Assembling a Protein Complex That Includes Ship2, Filamin and Lamellipodin
por: Venkatareddy, Madhusudan, et al.
Publicado: (2011)

Drosophila Pico and Its Mammalian Ortholog Lamellipodin Activate Serum Response Factor and Promote Cell Proliferation
por: Lyulcheva, Ekaterina, et al.
Publicado: (2008)

A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration
por: Lagarrigue, Frederic, et al.
Publicado: (2015)

Mouse Models of Gastric Cancer
por: Hayakawa, Yoku, et al.
Publicado: (2013)

The C5 Variant of the Butyrylcholinesterase Tetramer Includes a Noncovalently Bound 60 kDa Lamellipodin Fragment
por: Schopfer, Lawrence M., et al.
Publicado: (2017)

PtdIns(3,4)P(2), Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages
por: Montaño-Rendón, Fernando, et al.
Publicado: (2022)

Anaplastic nephroblastoma with peritoneal metastasis in an adult female Sprague Dawley rat
por: Quinn, Lisa, et al.
Publicado: (2020)

Translocation of Helicobacter hepaticus synergizes with myeloid-derived suppressor cells and contributes to breast carcinogenesis
por: Deng, Huan, et al.
Publicado: (2022)

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer
por: Dubeykovskaya, Zina, et al.
Publicado: (2016)

Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X
por: Pokrant, Thomas, et al.
Publicado: (2023)

Gastric Non-Helicobacter pylori Urease-Positive Staphylococcus epidermidis and Streptococcus salivarius Isolated from Humans Have Contrasting Effects on H. pylori-Associated Gastric Pathology and Host Immune Responses in a Murine Model of Gastric Cancer
por: Shen, Zeli, et al.
Publicado: (2022)

Intestinal Microbiota Composition of Interleukin-10 Deficient C57BL/6J Mice and Susceptibility to Helicobacter hepaticus-Induced Colitis
por: Yang, Ines, et al.
Publicado: (2013)

In-Vivo fluorescent nanosensor implants based on hydrogel-encapsulation: investigating the inflammation and the foreign-body response
por: Lee, Michael A., et al.
Publicado: (2023)

Enteric Infection with Citrobacter rodentium Induces Coagulative Liver Necrosis and Hepatic Inflammation Prior to Peak Infection and Colonic Disease
por: Raczynski, Arkadiusz R., et al.
Publicado: (2012)

Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense
por: Kumari, Puja, et al.
Publicado: (2021)

Analysis of gut microbiome profiles in common marmosets (Callithrix jacchus) in health and intestinal disease
por: Sheh, Alexander, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dum8s7tdv8buf7djh8e92g0nof