Cargando…
Geniposide Protects Primary Cortical Neurons against Oligomeric Aβ(1-42)-Induced Neurotoxicity through a Mitochondrial Pathway
Mitochondrial dysfunction plays a key role in the progression of Alzheimer’s disease (AD). The accumulation of amyloid-beta peptide (Aβ) in the brains of AD patients is thought to be closely related to neuronal mitochondrial dysfunction and oxidative stress. Therefore, protecting mitochondria from A...
Autores principales: | Zhao, Chunhui, Lv, Cui, Li, Hang, Du, Shijing, Liu, Xiaoli, Li, Zhi, Xin, Wenfeng, Zhang, Wensheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821580/ https://www.ncbi.nlm.nih.gov/pubmed/27046221 http://dx.doi.org/10.1371/journal.pone.0152551 |
Ejemplares similares
-
Geniposide Alleviates Amyloid-Induced Synaptic Injury by Protecting Axonal Mitochondrial Trafficking
por: Zhang, Haijing, et al.
Publicado: (2017) -
Endocytic pathways mediating oligomeric Aβ42 neurotoxicity
por: Yu, Chunjiang, et al.
Publicado: (2010) -
Conformational Essentials Responsible for Neurotoxicity of Aβ42 Aggregates Revealed by Antibodies against Oligomeric Aβ42
por: Song, Chuli, et al.
Publicado: (2022) -
Neuroprotective Effects of Geniposide in SH-SY5Y Cells and Primary Hippocampal Neurons Exposed to Aβ42
por: Sun, Ping, et al.
Publicado: (2014) -
Geniposide prevents rotenone-induced apoptosis in primary cultured neurons
por: Li, Lin, et al.
Publicado: (2015)