Cargando…

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T. cruzi infective process, transcriptome dynamics were simultaneously captured in the parasite and ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yuan, Shah-Simpson, Sheena, Okrah, Kwame, Belew, A. Trey, Choi, Jungmin, Caradonna, Kacey L., Padmanabhan, Prasad, Ndegwa, David M., Temanni, M. Ramzi, Corrada Bravo, Héctor, El-Sayed, Najib M., Burleigh, Barbara A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821583/ https://www.ncbi.nlm.nih.gov/pubmed/27046031 http://dx.doi.org/10.1371/journal.ppat.1005511

Ejemplares similares

Comparative Transcriptome Profiling of Human Foreskin Fibroblasts Infected with the Sylvio and Y Strains of Trypanosoma cruzi
por: Houston-Ludlam, Genevieve A., et al.
Publicado: (2016)

Modulation of host central carbon metabolism and in situ glucose uptake by intracellular Trypanosoma cruzi amastigotes
por: Shah-Simpson, Sheena, et al.
Publicado: (2017)

The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum
por: Won, Madalyn M., et al.
Publicado: (2023)

Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation
por: Dillon, Laura A. L., et al.
Publicado: (2015)

Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection
por: Belew, A. Trey, et al.
Publicado: (2017)

Stress-Induced Proliferation and Cell Cycle Plasticity of Intracellular Trypanosoma cruzi Amastigotes
por: Dumoulin, Peter C., et al.
Publicado: (2018)

Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions
por: Dillon, Laura A. L., et al.
Publicado: (2015)

Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes
por: Dumoulin, Peter C, et al.
Publicado: (2020)

DNA Methylation Patterns in Cord Blood of Neonates Across Gestational Age: Association With Cell-Type Proportions
por: Braid, Susan M., et al.
Publicado: (2017)

Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures
por: Fernandes, Maria Cecilia, et al.
Publicado: (2016)

Proximity-dependent biotinylation and identification of flagellar proteins in Trypanosoma cruzi
por: Won, Madalyn M., et al.
Publicado: (2023)

Proximity-Dependent Biotinylation and Identification of Flagellar Proteins in Trypanosoma cruzi
por: Won, Madalyn M., et al.
Publicado: (2023)

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation
por: Oliveira, Antonio Edson R., et al.
Publicado: (2020)

A Trypanosoma cruzi zinc finger protein that is implicated in the control of epimastigote-specific gene expression and metacyclogenesis
por: Tavares, Thais S., et al.
Publicado: (2021)

Impact of Laboratory-Adapted Intracellular Trypanosoma cruzi Strains on the Activity Profiles of Compounds with Anti-T. cruzi Activity
por: Sykes, Melissa L., et al.
Publicado: (2023)

Trypanosoma cruzi: mechanism of entry and intracellular fate in mammalian cells
Publicado: (1976)

Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection
por: Li, Xiaomo, et al.
Publicado: (2021)

Endogenous Sterol Synthesis Is Dispensable for Trypanosoma cruzi Epimastigote Growth but Not Stress Tolerance
por: Dumoulin, Peter C., et al.
Publicado: (2022)

Analysis and correction of compositional bias in sparse sequencing count data
por: Kumar, M. Senthil, et al.
Publicado: (2018)

Evaluation of Parameters Impacting Drug Susceptibility in Intracellular Trypanosoma cruzi Assay Protocols
por: Yang, Gyongseon, et al.
Publicado: (2016)

Disruption of Intracellular Calcium Homeostasis as a Therapeutic Target Against Trypanosoma cruzi
por: Benaim, Gustavo, et al.
Publicado: (2020)

Glutamine Analogues Impair Cell Proliferation, the Intracellular Cycle and Metacyclogenesis in Trypanosoma cruzi
por: Souza, Rodolpho Ornitz Oliveira, et al.
Publicado: (2020)

Endothelial Transmigration by Trypanosoma cruzi
por: Coates, Bria M., et al.
Publicado: (2013)

Profiling the Trypanosoma cruzi Phosphoproteome
por: Marchini, Fabricio K., et al.
Publicado: (2011)

Activity In Vivo of Anti-Trypanosoma cruzi Compounds Selected from a High Throughput Screening
por: Andriani, Grasiella, et al.
Publicado: (2011)

Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in Macrophages
por: Volpini, Ximena, et al.
Publicado: (2018)

Biological and Molecular Effects of Trypanosoma cruzi Residence in a LAMP-Deficient Intracellular Environment
por: Oliveira, Anny Carolline Silva, et al.
Publicado: (2022)

Genetic Diversity of Trypanosoma cruzi in Panama Inferred by Multi-locus Sequence Typing of Mitochondrial Genes
por: Calzada, Jose E., et al.
Publicado: (2022)

Identification of O-Glcnacylated Proteins in Trypanosoma cruzi
por: Torres-Gutiérrez, Elia, et al.
Publicado: (2019)

OBSERVATIONS ON THE RESPIRATION OF TRYPANOSOMA CRUZI IN CULTURE
por: von Brand, Theodor, et al.
Publicado: (1946)

Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region
por: Westenberger, Scott J, et al.
Publicado: (2006)

Flagellar Motility of Trypanosoma cruzi Epimastigotes
por: Ballesteros-Rodea, G., et al.
Publicado: (2012)

Clathrin expression in Trypanosoma cruzi
por: Kalb, Ligia Cristina, et al.
Publicado: (2014)

The N-myristoylome of Trypanosoma cruzi
por: Roberts, Adam J., et al.
Publicado: (2016)

A Cytosolic Serine Endopeptidase from Trypanosoma cruzi Is Required for the Generation of Ca(2+) Signaling in Mammalian Cells
por: Burleigh, Barbara A., et al.
Publicado: (1997)

Autochthonous Transmission of Trypanosoma cruzi, Louisiana
por: Dorn, Patricia L., et al.
Publicado: (2007)

Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture
por: Ferreira, Eden R., et al.
Publicado: (2021)

Trypanosoma cruzi Intracellular Amastigotes Isolated by Nitrogen Decompression Are Capable of Endocytosis and Cargo Storage in Reservosomes
por: Batista, Cassiano Martin, et al.
Publicado: (2015)

An Intracellular Ammonium Transporter Is Necessary for Replication, Differentiation, and Resistance to Starvation and Osmotic Stress in Trypanosoma cruzi
por: Cruz-Bustos, Teresa, et al.
Publicado: (2018)

Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi
por: Obado, Samson O, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_v2dnk5k6lo1j814biqdo7ob2k8