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Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19(+)CD24(hi)CD38(hi) Regulatory B-Lymphocytes
BACKGROUND: CD19(+)CD24(hi)CD38(hi) transitional immature B-lymphocytes have been demonstrated to play an important role in regulating the alloimmune response in transplant recipients. Here, we analyzed the effect of calcineurin inhibition on these peripherally circulating regulatory B-cells (Breg)...
Autores principales: | Tebbe, Bastian, Wilde, Benjamin, Ye, Zeng, Wang, Junyu, Wang, Xinning, Jian, Fu, Dolff, Sebastian, Schedlowski, Manfred, Hoyer, Peter F., Kribben, Andreas, Witzke, Oliver, Hoerning, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821620/ https://www.ncbi.nlm.nih.gov/pubmed/27045291 http://dx.doi.org/10.1371/journal.pone.0153170 |
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