Natalizumab-induced POU2AF1/Spi-B upregulation: A possible route for PML development

OBJECTIVES: To assess messenger RNA (mRNA) expression of POU2AF1 and Spi-B and their potential regulatory microRNAs (miRNAs) in natalizumab-treated patients with multiple sclerosis and in therapy-associated progressive multifocal leukoencephalopathy (PML). METHODS: Expression of POU2AF1/Spi-B was an...

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Detalles Bibliográficos
Autores principales: Meira, Maria, Sievers, Claudia, Hoffmann, Francine, Haghikia, Aiden, Rasenack, Maria, Décard, Bernhard F., Kuhle, Jens, Derfuss, Tobias, Kappos, Ludwig, Lindberg, Raija L.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821666/
https://www.ncbi.nlm.nih.gov/pubmed/27088119
http://dx.doi.org/10.1212/NXI.0000000000000223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821666/
https://www.ncbi.nlm.nih.gov/pubmed/27088119
http://dx.doi.org/10.1212/NXI.0000000000000223

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