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Multi-perspective smFRET reveals rate-determining late intermediates of ribosomal translocation
Directional translocation of the ribosome through the messenger RNA open reading frame is a critical determinant of translational fidelity. This process entails a complex interplay of large-scale conformational changes within the actively translating particle, which together coordinate the movement...
Autores principales: | Wasserman, Michael R., Alejo, Jose L., Altman, Roger B., Blanchard, Scott C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821728/ https://www.ncbi.nlm.nih.gov/pubmed/26926435 http://dx.doi.org/10.1038/nsmb.3177 |
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