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Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional changes associated with macrophage phenotype, but posttranscriptional control of...
Autores principales: | de Bruin, Ruben G., Shiue, Lily, Prins, Jurriën, de Boer, Hetty C., Singh, Anjana, Fagg, W. Samuel, van Gils, Janine M., Duijs, Jacques M. G. J., Katzman, Sol, Kraaijeveld, Adriaan O., Böhringer, Stefan, Leung, Wai Y., Kielbasa, Szymon M., Donahue, John P., van der Zande, Patrick H.J., Sijbom, Rick, van Alem, Carla M. A., Bot, Ilze, van Kooten, Cees, Jukema, J. Wouter, Van Esch, Hilde, Rabelink, Ton J., Kazan, Hilal, Biessen, Erik A. L., Ares Jr., Manuel, van Zonneveld, Anton Jan, van der Veer, Eric P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821877/ https://www.ncbi.nlm.nih.gov/pubmed/27029405 http://dx.doi.org/10.1038/ncomms10846 |
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