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HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation

Aging-induced cardiac dysfunction is a prominent feature of cardiac aging. Heat shock protein 27 (HSP27) protects cardiac function against ischemia or chemical challenge. We hypothesized that HSP27 attenuates cardiac aging. Transgenic (Tg) mice with cardiac-specific expression of the HSP27 gene and...

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Detalles Bibliográficos
Autores principales:	Lin, Shenglan, Wang, Yana, Zhang, Xiaojin, Kong, Qiuyue, Li, Chuanfu, Li, Yuehua, Ding, Zhengnian, Liu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821973/ https://www.ncbi.nlm.nih.gov/pubmed/27110324 http://dx.doi.org/10.1155/2016/2586706

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