Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo

Neutrophils are terminally differentiated cells with limited transcriptional activity. The biological function of their gene expression changes is poorly understood. CARD9 regulates transcription during antifungal immunity but its role in sterile inflammation is unclear. Here we show that neutrophil...

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Detalles Bibliográficos
Autores principales: Németh, Tamás, Futosi, Krisztina, Sitaru, Cassian, Ruland, Jürgen, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821996/
https://www.ncbi.nlm.nih.gov/pubmed/27032818
http://dx.doi.org/10.1038/ncomms11004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821996/
https://www.ncbi.nlm.nih.gov/pubmed/27032818
http://dx.doi.org/10.1038/ncomms11004

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