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Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

Preventing xenograft rejection is one of the greatest challenges of transplantation medicine. Here, we describe a reproducible, long-term survival of cardiac xenografts from alpha 1-3 galactosyltransferase gene knockout pigs, which express human complement regulatory protein CD46 and human thrombomo...

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Detalles Bibliográficos
Autores principales:	Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Thomas III, Marvin L., Clark, Tannia, Lewis, Billeta G., Hoyt, Robert F., Eckhaus, Michael, Pierson III, Richard N., Belli, Aaron J., Wolf, Eckhard, Klymiuk, Nikolai, Phelps, Carol, Reimann, Keith A., Ayares, David, Horvath, Keith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822024/ https://www.ncbi.nlm.nih.gov/pubmed/27045379 http://dx.doi.org/10.1038/ncomms11138

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