Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While macaques synthesize the sialic acid variant N-glycolylneuraminic acid (Neu5Gc), h...

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Detalles Bibliográficos
Autores principales: Dankwa, Selasi, Lim, Caeul, Bei, Amy K., Jiang, Rays H. Y., Abshire, James R., Patel, Saurabh D., Goldberg, Jonathan M., Moreno, Yovany, Kono, Maya, Niles, Jacquin C., Duraisingh, Manoj T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822025/
https://www.ncbi.nlm.nih.gov/pubmed/27041489
http://dx.doi.org/10.1038/ncomms11187

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