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A general strategy for expanding polymerase function by droplet microfluidics

Polymerases that synthesize artificial genetic polymers hold great promise for advancing future applications in synthetic biology. However, engineering natural polymerases to replicate unnatural genetic polymers is a challenging problem. Here we present droplet-based optical polymerase sorting (DrOP...

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Detalles Bibliográficos
Autores principales: Larsen, Andrew C., Dunn, Matthew R., Hatch, Andrew, Sau, Sujay P., Youngbull, Cody, Chaput, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822039/
https://www.ncbi.nlm.nih.gov/pubmed/27044725
http://dx.doi.org/10.1038/ncomms11235