Connexins and pannexins in liver damage

Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxic...

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Autores principales: Crespo Yanguas, Sara, Willebrords, Joost, Maes, Michaël, da Silva, Tereza Cristina, Veloso Alves Pereira, Isabel, Cogliati, Bruno, Zaidan Dagli, Maria Lucia, Vinken, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822047/
https://www.ncbi.nlm.nih.gov/pubmed/27065778
http://dx.doi.org/10.17179/excli2016-119
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author Crespo Yanguas, Sara
Willebrords, Joost
Maes, Michaël
da Silva, Tereza Cristina
Veloso Alves Pereira, Isabel
Cogliati, Bruno
Zaidan Dagli, Maria Lucia
Vinken, Mathieu
author_facet Crespo Yanguas, Sara
Willebrords, Joost
Maes, Michaël
da Silva, Tereza Cristina
Veloso Alves Pereira, Isabel
Cogliati, Bruno
Zaidan Dagli, Maria Lucia
Vinken, Mathieu
author_sort Crespo Yanguas, Sara
collection PubMed
description Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets.
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spelling pubmed-48220472016-04-08 Connexins and pannexins in liver damage Crespo Yanguas, Sara Willebrords, Joost Maes, Michaël da Silva, Tereza Cristina Veloso Alves Pereira, Isabel Cogliati, Bruno Zaidan Dagli, Maria Lucia Vinken, Mathieu EXCLI J Review Article Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets. Leibniz Research Centre for Working Environment and Human Factors 2016-02-25 /pmc/articles/PMC4822047/ /pubmed/27065778 http://dx.doi.org/10.17179/excli2016-119 Text en Copyright © 2016 Crespo Yanguas et al. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/) You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Review Article
Crespo Yanguas, Sara
Willebrords, Joost
Maes, Michaël
da Silva, Tereza Cristina
Veloso Alves Pereira, Isabel
Cogliati, Bruno
Zaidan Dagli, Maria Lucia
Vinken, Mathieu
Connexins and pannexins in liver damage
title Connexins and pannexins in liver damage
title_full Connexins and pannexins in liver damage
title_fullStr Connexins and pannexins in liver damage
title_full_unstemmed Connexins and pannexins in liver damage
title_short Connexins and pannexins in liver damage
title_sort connexins and pannexins in liver damage
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822047/
https://www.ncbi.nlm.nih.gov/pubmed/27065778
http://dx.doi.org/10.17179/excli2016-119
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