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QSAR study of HCV NS5B polymerase inhibitors using the genetic algorithm-multiple linear regression (GA-MLR)

Quantitative structure-activity relationship (QSAR) study has been employed for predicting the inhibitory activities of the Hepatitis C virus (HCV) NS5B polymerase inhibitors. A data set consisted of 72 compounds was selected, and then different types of molecular descriptors were calculated. The wh...

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Detalles Bibliográficos
Autores principales:	Rafiei, Hamid, Khanzadeh, Marziyeh, Mozaffari, Shahla, Bostanifar, Mohammad Hassan, Avval, Zhila Mohajeri, Aalizadeh, Reza, Pourbasheer, Eslam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822051/ https://www.ncbi.nlm.nih.gov/pubmed/27065774 http://dx.doi.org/10.17179/excli2015-731

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