Cargando…
Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency
Mechanisms driving persistent airway inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. As secretory immunoglobulin A (SIgA) deficiency in small airways has been reported in COPD patients, we hypothesized that immunobarrier dysfunction resulting from reduced SI...
Autores principales: | Richmond, Bradley W., Brucker, Robert M., Han, Wei, Du, Rui-Hong, Zhang, Yongqin, Cheng, Dong-Sheng, Gleaves, Linda, Abdolrasulnia, Rasul, Polosukhina, Dina, Clark, Peter E., Bordenstein, Seth R., Blackwell, Timothy S., Polosukhin, Vasiliy V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822073/ https://www.ncbi.nlm.nih.gov/pubmed/27046438 http://dx.doi.org/10.1038/ncomms11240 |
Ejemplares similares
-
Small airway determinants of airflow limitation in chronic obstructive pulmonary disease
por: Polosukhin, Vasiliy V, et al.
Publicado: (2021) -
Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis
por: Novitskiy, Sergey V., et al.
Publicado: (2019) -
Environmental and occupational bronchiolitis obliterans: new reality
por: Gutor, Sergey S., et al.
Publicado: (2023) -
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD
por: Richmond, Bradley W., et al.
Publicado: (2020) -
p52 expression enhances lung cancer progression
por: Saxon, Jamie A., et al.
Publicado: (2018)