A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity

OBJECTIVES: Acetaminophen (APAP)-induced hepatotoxicity is a major cause of morbidity and mortality. The current pharmacologic treatment for APAP hepatotoxicity, N-acetyl cysteine (NAC), targets the initial metabolite-driven injury but does not directly affect the host inflammatory response. Because...

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Detalles Bibliográficos
Autores principales: Patel, Suraj J, Luther, Jay, Bohr, Stefan, Iracheta-Vellve, Arvin, Li, Matthew, King, Kevin R, Chung, Raymond T, Yarmush, Martin L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822092/
https://www.ncbi.nlm.nih.gov/pubmed/26986653
http://dx.doi.org/10.1038/ctg.2016.13

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