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Combined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia

Modelling the parameters of multistep carcinogenesis is key for a better understanding of cancer progression, biomarker identification and the design of individualized therapies. Using chronic myeloid leukemia (CML) as a paradigm for hierarchical disease evolution we show that combined population dy...

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Detalles Bibliográficos
Autores principales: Brehme, Marc, Koschmieder, Steffen, Montazeri, Maryam, Copland, Mhairi, Oehler, Vivian G., Radich, Jerald P., Brümmendorf, Tim H., Schuppert, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822142/
https://www.ncbi.nlm.nih.gov/pubmed/27048866
http://dx.doi.org/10.1038/srep24057