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Combined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia
Modelling the parameters of multistep carcinogenesis is key for a better understanding of cancer progression, biomarker identification and the design of individualized therapies. Using chronic myeloid leukemia (CML) as a paradigm for hierarchical disease evolution we show that combined population dy...
Autores principales: | Brehme, Marc, Koschmieder, Steffen, Montazeri, Maryam, Copland, Mhairi, Oehler, Vivian G., Radich, Jerald P., Brümmendorf, Tim H., Schuppert, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822142/ https://www.ncbi.nlm.nih.gov/pubmed/27048866 http://dx.doi.org/10.1038/srep24057 |
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